Targeting dormant cancer cells might open door to metastasis prevention

Interview with Prof. Julio Aguierre-Ghiso on the clinical impact of new insights into metastasis formation. Metastasis and primary tumor growth can be initiated simultaneously.

Interview with Prof. Julio Aguierre-Ghiso on the clinical impact of new insights into metastasis formation.

Metastasis and primary tumor growth can be initiated simultaneously. Oncogenes and tumor suppressors alter mechanisms linked to cell movement and cell survival, before causing frank tumor growth. And a paradigm shift becomes apparent: metastases do not necessarily originate from small subpopulations of cells present in large invasive tumors. In this interview keynote speaker Prof. Julio Aguierre-Ghiso, Icahn School of Medicine at Mount Sinai, New York (USA) summarizes the clinical impact of new insights into metastasis formation.